Cellular senescence and chromatin organisation
نویسندگان
چکیده
منابع مشابه
Chromatin remodeling, BRCA1, SAHF and cellular senescence
Cellular senescence is a state of stable cell growth arrest. Activation of oncogenes in primary mammalian cells typically triggers cellular senescence. Oncogeneinduced senescence is an important tumor suppression mechanism, driving stable growth arrest of cancer progenitor cells harboring the initial oncogenic hit. Chromatin in the nuclei of senescent human cells is often reorganized to form sp...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 2007
ISSN: 0007-0920,1532-1827
DOI: 10.1038/sj.bjc.6603636